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modified on 29 April 2009 at 03:05 ••• 2,991 views

Camazepam

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Camazepam is sold under the brands Albego, Limpidon, and Paxor.


Summary of clinical effects, Camazepam

Central nervous system (CNS) depression and coma, or paradoxical excitation, but deaths are rare when benzodiazepines are taken alone. Deep coma and other manifestations of severe CNS depression are rare. Sedation, somnolence, diplopia, dysarthria, ataxia and intellectual impairment are the most common adverse effects of benzodiazepines. Overdose in adults frequently involves co-ingestion of other CNS depressants, which act synergistically to increase toxicity. Elderly and very young children are more susceptible to the CNS depressant action. Intravenous administration of even therapeutic doses of benzodiazepines may produce apnoea and hypotension. Dependence may develop with regular use of benzodiazepines, even in therapeutic doses for short periods. If benzodiazepines are discontinued abruptly after regular use, withdrawal symptoms may develop. The amnesia produced by benzodiazepines can have medico-legal consequences.

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Camazepam
Systematic (IUPAC) name
(9-chloro- 2-methyl- 3-oxo- 6-phenyl- 2,5-diazabicyclo [5.4.0]undeca- 5,8,10,12-tetraen- 4-yl) N,N-dimethylcarbamate
Identifiers
CAS number 36104-80-0
ATC code N05BA15
PubChem 37367
DrugBank ?
Chemical data
Formula C19H18ClN3O3 
Mol. mass 371.8
Pharmacokinetic data
Bioavailability  ?
Metabolism Hepatic
Half life  ?
Excretion Renal
Therapeutic considerations
Pregnancy cat.

?

Legal status

Schedule IV(US)

Routes Oral