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modified on 29 April 2009 at 04:35 ••• 4,022 views

Doxefazepam

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Doxefazepam is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. According to Babbini and colleagues in 1975, this derivative of flurazepam was between 2 and 4 times more potent than the latter while at the same time being half as toxic.

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Doxefazepam
Systematic (IUPAC) name
9-chloro-6-(2-fluorophenyl)-4-hydroxy
-2-(2-hydroxyethyl)-2,5-diazabicyclo
[5.4.0]undeca-5,8,10,12-tetraen-3-one
Identifiers
CAS number 40762-15-0
ATC code N05CD12
PubChem 38668
DrugBank ?
Chemical data
Formula C17H14ClFN2O3 
Mol. mass 348.8
Pharmacokinetic data
Bioavailability  ?
Metabolism Hepatic
Half life 3-4 hours[1]
Excretion Renal
Therapeutic considerations
Pregnancy cat.

?

Legal status

Schedule IV(US)

Routes Oral


Brand names

  • Doxans