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modified on 17 June 2009 at 01:04 ••• 5,538 views

Methadone

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Methadone is a narcotic pain reliever, similar to morphine. It also reduces withdrawal symptoms in people addicted to heroin or other narcotic drugs without causing the same "high". (Note that it does give you a high if you are not a constant heroin user, or using similiar drugs at daily basis). Methadone is a synthetic opiate derivative

Methadone is also used as a pain reliever and as part of drug addiction detoxification (as Buprenorphine) and maintenance programs. Methadone may also be used recreational purposes.


Contents

Methadone other names

  • Symoron
  • Dolophine
  • Amidone
  • Methadose
  • Physeptone
  • Heptadon
  • Juice


Chemical name for Methadone

6-dimethylamino-4,4-diphenyl-3-heptanone

Methadone.svg.png
Methadone
Systematic (IUPAC) name
6-(Dimethylamino)-4,4-diphenylheptan-3-one
Identifiers
CAS number 76-99-3
ATC code N02AC52 N07BC02, R05DA06
PubChem 4095
DrugBank APRD00485
ChemSpider 3953
Chemical data
Formula C21H27NO 
Mol. mass 309.445 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability 40-90%
Metabolism Hepatic
Half life 24-36 h
Excretion Urine, Test by specific gravity and bilirubin
Therapeutic considerations
Pregnancy cat.

Reduction of oxygen to unborn child due to depression of breathing

Legal status

Class A(UK) Schedule II(US)

Dependence Liability Moderate
Routes oral, intravenous, insufflation

Methadone and Urine Testing

Methadone does not show up in a basic opiate test that is part of the standard pre-employment drug test and which can detect heroin, codeine and morphine (and perhaps oxycodone, hydrocodone, and dilaudid). A Methadone specific test must be performed to detect Methadone. This test is not uncommon and is part of the second tier "extended" test done by many companies. In such Methadone specific tests it can be detected UP TO seven days after consume but that is out of the ordinary, normally it's gone after a few days.


About Methadone by Mcdermott

To cater for those of us seeking to starve the dealers, a newer product is becoming more widely available. Methadone was originally developed by the Nazi's during World War II. When the supply of opium was cut off, Nazi smackheads like Goering wanted to avoid the possibility of withdrawal, so he instructed the German drug companies to produce a wholly synthetic opiate that didn't need to rely on the poppy. With typical Teutonic efficiency, the chemists came up with a drug that not only worked, but also lasted a long time. As a result, Methadone has become the drug of choice for doctors who are trying to help users manage their opiate dependency. Heroin wears off after a couple of hours, thus requiring several hits each day. Methadone, on the other hand, lasts anywhere between 24 and 72 hours, depending on the dose that you take and on your individual metabolism.

Methadone comes in several forms

  • 10mg ampoules
  • 5 mg tablets, Methadone
  • Linctus - 1 mg in 2.5 ml
  • Methadone Mixture DTF - 1 mg in 1 ml.

Again, very rarely somebody will break into a chemist and pharmaceutical methadone powder will come onto the market. This stuff is very, very strong, so if you ever happen to come across it, be extremely careful how much you use, especially if you are only used to street smack.

Many users claim that the problem with methadone is that it lacks heroin's intensity. It doesn't give you the same rush when injected and many users believe that the high is inferior compared to heroin. How much of this resistance to methadone is psychological is unclear. Many users become obsessed with the rituals of drug use - cooking up a hit, or rolling a bead around the foil.

In blind trials, users who were given both drugs orally were unable to distinguish between the effects of the two drugs. Where heroin does have a real advantage over methadone is in withdrawal. Withdrawal from heroin should be over after seven to ten days. Withdrawal from methadone though, can take up to a month or even longer.

Any discussion of the properties of Methadone must also be an appropriate place to warn of the dangers of Cyclazine. In an attempt to replicate the effects of a now almost defunct drug called Diconal, desperadoes of the drug scene have been known to mix certain travel sickness pills with methadone ampoules before injecting them in an attempt to produce a Diconal-like rush. In fact, the use of this combination just produces self- destructive Martians whom all right-thinking junkies shun because of their tendency towards compulsive and chaotic behaviour. In the past, I have watched many a time-served junkie who after managing to keep it together for many years, eventually fell to pieces after discovering Cyclazine. Hopefully, as the Diconal experience retreats further and further back into the annals of folk memory, fewer people will experiment with this combination, but until then, I can only make one recommendation with regard to this substance - avoid it like HIV (or the plague.)

  • Reference - McDermott's Guide to the Depressant Drugs