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modified on 29 April 2009 at 07:52 ••• 5,623 views

Phenazepam

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Phenazepam was developed in Soviet Union and now produced in Russia and some CIS countries. Phenazepam is used in the treatment of neurological disorders such as epilepsy, alcohol withdrawal syndrome and insomnia. It can be used as a premedication before surgery as it augments the effects of anesthetics and reduces anxiety.

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Phenazepam
Systematic (IUPAC) name
7-bromo- 5-(2-chlorophenyl)- 1,3-dihydro- 2H- 1,4-benzodiazepin- 2-one
Identifiers
CAS number 51753-57-2
ATC code  ?
PubChem 40113
Chemical data
Formula C15H10BrClN2O 
Mol. mass 349.609
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 60 hours[1]
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?


Dosage Phenazepam

An average phenazepam dosage is 0.5 mg 2-3 times daily. The maximum daily dosage must not exceed 10 mg.


Phenazepam side effects

Side effects include dizziness, loss of coordination and drowsiness, along with anterograde amnesia which can be quite pronounced at high doses. As with other benzodiazepines, in case of abrupt discontinuation following prolonged use, severe withdrawal symptoms may occur including restlessness, anxiety, insomnia and convulsions.