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Talk:Amisulpride - Revision history
2026-06-04T16:37:14Z
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Sysop: 1 revision imported
2025-11-01T14:11:35Z
<p>1 revision imported</p>
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Sysop
https://www.drugwiki.net/wen/index.php?title=Talk:Amisulpride&diff=8838&oldid=prev
en>Blackhole: fixed link
2024-04-30T13:14:13Z
<p>fixed link</p>
<p><b>New page</b></p><div>{{headerpanel|{{Approval}}}}<br />
{{SummarySheet}}<br />
{{SubstanceBox/Amisulpride}}<br />
'''Amisulpride''' (also known under brand names including '''Solian''' and '''Barhemsys''') is a atypical [[psychoactive class::antipsychotic]] substance of the [[chemical class::benzamide]] class.<br />
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==History and culture==<br />
{{historyStub}}<br />
<br />
==Chemistry==<br />
{{chemistry}}<br />
Amisulpride is the 4-position amino substitution of [[sulpiride]] which in turn is based on a [[chemical class::benzamide]] core.<br />
<br />
==Pharmacology==<br />
Amisulpride primarily works by antagonising D<sub>2</sub> and D<sub>3</sub> [[dopamine]] receptors aswell as the 5-HT<sub>7</sub>, 5-HT<sub>2A</sub> and 5-HT<sub>2B</sub> [[serotonin]] receptors.<br />
<br />
It is also known to act as a [[GHB receptor]] agonist and Mu- Delta- Kappa-[[opioid]] agonist<ref>Rehni AK, Singh TG, Chand P: Amisulpride-induced seizurogenic effect: a potential role of opioid receptor-linked transduction systems. Basic Clin Pharmacol Toxicol. 2011 May;108(5):310-7. doi: 10.1111/j.1742-7843.2010.00655.x. Epub 2010 Dec 22. (PubMed ID 21176108)</ref><br />
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==Subjective effects==<br />
{{EffectStub}}<br />
{{Preamble/SubjectiveEffects}}<br />
{{effects/base<br />
<br />
|{{effects/physical|<br />
<br />
*'''[[Effect::Sedation]]'''<br />
*'''[[Effect::Increased salivation]]'''<br />
*'''[[Effect::Headaches]]'''<br />
*'''[[Effect::Nausea]]'''<br />
*'''[[Effect::Vomiting]]'''<br />
*'''[[Effect::Dry mouth]]''' anti-cholinergic effect<br />
*'''[[Effect::Constipation]]''' anti-cholinergic effect<br />
*'''[[Effect::Increased prolactin]]''' potentially causing the absence of the menstrual cycle, breast enlargement, breast milk secretion not related to breastfeeding, impaired fertility, impotence, breast pain, etc<br />
<br />
}}<br />
|{{effects/cognitive|<br />
<br />
*'''[[Effect::Thought deceleration]]''' <br />
*'''[[Effect::Thought acceleration]]''' contradictory side effect<br />
*'''[[Effect::Dream potentiation]]''' <br />
<br />
}}<br />
}}<br />
===Experience reports===<br />
There are currently {{#ask:[[Category:SUBSTANCE]][[Category:Experience]] | format=count}} experience reports which describe the effects of this substance in our [[experience index]].<br />
{{#ask: [[Category:SUBSTANCE]][[Category:Experience]]|format=ul|Columns=1}}<br />
Additional experience reports can be found here:<br />
* [https://erowid.org/experiences/subs/exp_Amisulpride.shtml Erowid Experience Vaults: Amisulpride]<br />
<br />
==Toxicity and harm potential==<br />
{{toxicity}}<br />
It is strongly recommended that one use [[responsible use|harm reduction practices]] when using this substance.<br />
===Lethal dosage===<br />
===Tolerance and addiction potential===<br />
===Dangerous interactions===<br />
{{DangerousInteractions}}<br />
{{DangerousInteractions/Intro}}<br />
<br />
==Legal status==<br />
{{LegalStub}}<br />
*'''Australia''': Amisulpride is a Schedule 4 prescription only drug.{{citation needed}}<br />
*'''Brazil''': Amisulpride is a Class C1 prescription only drug.<ref>https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992</ref><br />
*'''United Kingdom''': Amisulpride is a prescription only drug.<ref>https://web.archive.org/web/20200226225750/https://www.medicines.org.uk/emc/product/2726/smpc</ref><br />
*'''United States''': Amisulpride is a prescription only drug.{{citation needed}}<br />
<br />
==See also==<br />
*[[Responsible use]]<br />
<br />
==External links==<br />
*[https://en.wikipedia.org/wiki/Amisulpride Amisulpride (Wikipedia)]<br />
*[https://isomerdesign.com/PiHKAL/explore.php?id=9407 Amisulpride (Isomer Design)]<br />
*[https://go.drugbank.com/drugs/DB06288 Amisulpride (DrugBank)]<br />
*[https://www.drugs.com/mtm/amisulpride.html#dosage Amisulpride (Drugs.com)]<br />
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==References==<br />
<references /><br />
<br />
[[Category:Benzamide]]<br />
[[Category:Antipsychotic]]<br />
[[Category:Atypical Neuroleptic]]<br />
[[Category:Opioid]]<br />
[[Category:Benzamide]]<br />
[[Category:Psychoactive substance]]<br />
<br />
[[Category:Proofread]]<br />
[[Category:Approval]]</div>
en>Blackhole