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Summary sheet: Amisulpride
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Amisulpride
Chemical Nomenclature
Common names common name::Amisulpride, common name::Solian, common name::Barhemsys
Systematic name [[systematic name::4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamide]]
Class Membership
Psychoactive class psychoactive class::Antipsychotic
Chemical class chemical class::Benzamide
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.



{{#arrayunique: OralDosage}} {{#loop: i | 0 | {{#arraysize: OralDosage}} | {{#arraydefine: val | {{#arrayindex: OralDosage | {{#var: i}} }} | ; }} }} {{#arrayunique: OralDuration}} {{#loop: i | 0 | {{#arraysize: OralDuration}} | {{#arraydefine: val | {{#arrayindex: OralDuration | {{#var: i}} }} | ; }} }}
⇣ Oral
Dosage
Bioavailability Oral bioavailability::48%
[[Dosage_classification#{{#arrayindex: val | 0 }}|{{#arrayindex: val | 0 }}]] {{#arrayindex: val | 1 }}
Duration
[[Duration#{{#arrayindex: val | 0 }}|{{#arrayindex: val | 0 }}]] {{#arrayindex: val | 1 }}









DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

Interactions
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Amisulpride (also known under brand names including Solian and Barhemsys) is a atypical psychoactive class::antipsychotic substance of the chemical class::benzamide class.

History and culture

This History and culture section is a stub.

As a result, it may contain incomplete or wrong information. You can help by expanding it.

Chemistry

This chemistry section is incomplete.

You can help by adding to it.

Amisulpride is the 4-position amino substitution of sulpiride which in turn is based on a chemical class::benzamide core.

Pharmacology

Amisulpride primarily works by antagonising D2 and D3 dopamine receptors aswell as the 5-HT7, 5-HT2A and 5-HT2B serotonin receptors.

It is also known to act as a GHB receptor agonist and Mu- Delta- Kappa-opioid agonist[1]

Subjective effects

This subjective effects section is a stub.

As such, it is still in progress and may contain incomplete or wrong information.

You can help by expanding or correcting it.

Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism.

It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.

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Experience reports

There are currently {{#ask: | format=count}} experience reports which describe the effects of this substance in our experience index. {{#ask: |format=ul|Columns=1}} Additional experience reports can be found here:

Toxicity and harm potential

This toxicity and harm potential section is a stub.

As a result, it may contain incomplete or even dangerously wrong information! You can help by expanding upon or correcting it.
Note: Always conduct independent research and use harm reduction practices if using this substance.

It is strongly recommended that one use harm reduction practices when using this substance.

Lethal dosage

Tolerance and addiction potential

Dangerous interactions

This dangerous interactions section is a stub.

As such, it may contain incomplete or invalid information. You can help by expanding upon or correcting it.

Warning: Many psychoactive substances that are reasonably safe to use on their own can suddenly become dangerous and even life-threatening when combined with certain other substances. The following list provides some known dangerous interactions (although it is not guaranteed to include all of them).

Always conduct independent research (e.g. Google, DuckDuckGo, PubMed) to ensure that a combination of two or more substances is safe to consume. Some of the listed interactions have been sourced from TripSit.

Legal status

This legality section is a stub.

As such, it may contain incomplete or wrong information. You can help by expanding it.

  • Australia: Amisulpride is a Schedule 4 prescription only drug.[citation needed]
  • Brazil: Amisulpride is a Class C1 prescription only drug.[2]
  • United Kingdom: Amisulpride is a prescription only drug.[3]
  • United States: Amisulpride is a prescription only drug.[citation needed]

See also

External links

References

  1. ↑ Rehni AK, Singh TG, Chand P: Amisulpride-induced seizurogenic effect: a potential role of opioid receptor-linked transduction systems. Basic Clin Pharmacol Toxicol. 2011 May;108(5):310-7. doi: 10.1111/j.1742-7843.2010.00655.x. Epub 2010 Dec 22. (PubMed ID 21176108)
  2. ↑ https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992
  3. ↑ https://web.archive.org/web/20200226225750/https://www.medicines.org.uk/emc/product/2726/smpc