modified on 8 July 2009 at 20:22 ••• 12,902 views


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MDPV is a smartdrug, meaning it is legal in some countries. MDPV stands for Methylenedioxypyrovalerone and is also known as MDPK.

Systematic (IUPAC) name
CAS number 687603-66-3 24622-62-6 (Hydrochloride)
ATC code  ?
PubChem 20111961
Chemical data
Formula C16H21NO3 
Mol. mass 275.35 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.


Legal status

unscheduled (illegal in Denmark)

Routes oral, insufflation, intravenous

Subjective effects include CNS stimulation, euphoria, hypersexuality, agitation/anxiety and insomnia, with a duration of three to six hours. High doses have been observed to cause intense, prolonged anxiety attacks in stimulant-intolerant users, and there are anecdotal reports of addiction at higher doses or more frequent dosing intervals. MDPV has been remarked about more than once for its powers as an aphrodisiac, which have been said to rival those of methamphetamine when dosed correctly. However, it is apparently not as powerful as meth as far as general effects go, and may be safer (there have been no reports of death or disability as a result of abuse posted on "research chemical" related internet forums, and these tend to surface rapidly when a substance poses immediate dangers).

MDPV is the 3,4-methylenedioxy ring-substituted analogue of the appetite suppressant pyrovalerone, however despite its apparent structural similarity to the untrained eye, the effects of MDPV bear little resemblance to other methylenedioxyphenylalkylamine derivatives such as MDMA and methylone, instead producing purely stimulant effects with no empathogenic qualities. Extended binges on MDPV have also been reported to produce severe come-down syndrome similar to that of methamphetamine and characterised by depression, lethargy and headache.

MDPV is only listed as a ilegal drug in Denmark so far, but its structural similarity to illegal drugs of abuse makes it likely that it would be considered a controlled substance analogue in several countries such as the USA, Australia and New Zealand. Other analogues derived from alpha-pyrrolidinopropiophenone include the 4-methyl analogue pyrovalerone, as well as analogues with no substitution on the aromatic ring, and analogues with between 3 and 6 carbons on the alkyl chain. These compounds have been reported as stimulants of abuse mainly in Germany and other european countries since the early 2000s, but they have remained little known and rarely used or encountered by law enforcement. MDPV was never sold online in large quantities.

  • Swedish flag.gif Om MDPV på Svenska