modified on 7 April 2009 at 04:05 ••• 7,346 views


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PCP or Phencyclidine. PCP is available as powder and liquid forms. Often sprayed onto leafy material such as marijuana, mint, oregano, parsley, or ginger leaves or other "weedy" materials, and then smoked.

Using PCP

PCP is well absorbed when taken orally, intranasally, or IV, although oral ingestion is the slowest route to the CNS. PCP is stored in fat tissue and brain tissue, so although blood levels peak 1-4 hours after ingestion, PCP can be detected in urine up to 1 week following high dose use. At doses from 1-5 mg, PCP often seems like very potent marijuana. Above 5 mg, the effects are much less predictable. At 20 mg and above, hypertension, muscle rigidity, seizure, depressed breathing, coma and death can occur. Effects of higher doses include a withdrawn catatonic state, ataxia, dysarthria, muscular hypertonicity, and myoclonic jerks. Rotatory nystagmus is often present and helps in making the diagnosis. Cardio- vascular status is usually unaffected. Prolonged psychotic states have apparently followed use of this drug.

Other names for PCP

  • Angel Dust
  • Moon dust
  • Sherms
  • Embalming Fluid
Systematic (IUPAC) name
CAS number 77-10-1
ATC code  ?
PubChem 6468
ChemSpider 6224
Chemical data
Formula C17H25N 
Mol. mass 243.387 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 7-46 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.


Legal status

Schedule II / Class A

Routes Smoked, Insufflated, Oral

Synthesis process PCP

The manufacture of PCP is a two-stage reaction. First, PCC (1-piperidinocyclohexanecarbonitrile) is created by reacting piperidine, cyanide, and cyclohexanone. This product is then reacted with phenylmagnesium bromide to form the final product. The total reaction time for completion requires 16 to 18 hours.