MMDA
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Generell information
MMDA kan skapas genom aminering av den eteriska oljan myristicin.
Claudio Naranjo skriver i boken "The Healing Journey" om sin forkning om MMDA som verktyg i psykedelisk terapi. MMDA besitter önskvärda egenskaper för detta ändamålet. Kapitlet kan läsas i källa (3).
MMDA är narkotikaklassad i Sverige.
Effekt / dosering
Effekten liknar inte den som "kusinerna" MDA och MDMA ger. MMDA ger mindre stimulering, mera CEV:s och effekten är drömlik.
Oral dosering: 100 - 250 mg
"(Om muskotolja:) The substance myristicin is the major component of this fraction, and if it were to undergo the transformation parallel to that proposed for elemicin, a second amphetamine, 3-methoxy-4,5-methylenedioxy amphetamine (MMDA), would result."
"This latter amphetamine has been synthesized from myristicin in vitro, by a three-step process. trans-Isomyristicin, obtained from myristicin by heating in alcoholic potassium hydroxide, is converted by means of tetranitromethane to ß-nitro isomyristicin. Reduction of this nitropropene with LiAlH4 led smoothly to MMDA, which was isolated as the hydrochloride. Examination of MMDA in mice and dogs displayed a behavioural and toxicological pattern similar to that of TMA, both quantitatively and qualitatively. Preliminary human evaluation revealed initial intoxication at about 1.0 mg/kg (as free base). More extensive assay has confirmed a thoroughly effective hypnogogic dementia at less than 2.0 mg/kg. The psychotomimetic syndrome was complete at this level: increased dosages (to 3.2 mg/kg) merely prolonged the duration of the episode. Thus the potency of MMDA is somewhat greater than TMA and nearly three times greater than mescaline." Källa: (1)
Kemi
 | Systematiskt namn | 3-metoxi-4,5-metylendioxyamfetamin |
|---|---|---|
| Trivialnamn | MMDA | |
| Kemisk formel | C11H15NO3 | |
| Smältpunkt | 133-134 °C (HCl) | |
| Kokpunkt | ||
| Molmassa | 209.2417 g/mol | |
| Densitet | ||
| Löslighet | Läs under extrahering |
LD50 ligger någonstna runt 100mg/kg (2)
Isomer:
- MMDA-2 (2-Metoxi-4,5-metylendioxyamfetamin
- MMDA-3a (2-Metoxi-3,4-metylendioxyamfetamin
- MMDA-3b (4-Metoxi-2,3-metylendioxyamfetamin
Externa länkar
(1) 3-Methoxy-4,5-methylenedioxy Amphetamine a New Psychotomimetic Agent
(2) Animal Pharmacology and Human Psychopharmacology of MMDA