Phenazepam
From Drugwiki - Information about drugs, steroids and medicine
Phenazepam was developed in Soviet Union and now produced in Russia and some CIS countries. Phenazepam is used in the treatment of neurological disorders such as epilepsy, alcohol withdrawal syndrome and insomnia. It can be used as a premedication before surgery as it augments the effects of anesthetics and reduces anxiety.
| |
| |
| Phenazepam
| |
| Systematic (IUPAC) name | |
| 7-bromo- 5-(2-chlorophenyl)- 1,3-dihydro- 2H- 1,4-benzodiazepin- 2-one | |
| Identifiers | |
| CAS number | |
| ATC code | ? |
| PubChem | |
| Chemical data | |
| Formula | C15H10BrClN2O |
| Mol. mass | 349.609 |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | 60 hours[1] |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
Dosage Phenazepam
An average phenazepam dosage is 0.5 mg 2-3 times daily. The maximum daily dosage must not exceed 10 mg.
Phenazepam side effects
Side effects include dizziness, loss of coordination and drowsiness, along with anterograde amnesia which can be quite pronounced at high doses. As with other benzodiazepines, in case of abrupt discontinuation following prolonged use, severe withdrawal symptoms may occur including restlessness, anxiety, insomnia and convulsions.